RESUMO O objetivo deste estudo é analisar o perfil clínico-hospitalar de neonatos com o diagnóstico de hérnia diafragmática congênita (HDC), no período de 2008 a 2018 em um hospital de referência materno-infantil. Trata-se de um estudo transversal e analítico descritivo, que incluiu principalmente dados de prontuários com os códigos Q79.0, Q79.1, J986, K44 e K44.0 da Classificação Internacional de Doenças (CID-10). Os critérios de exclusão de prontuários foram o diagnóstico de outros tipos de hérnia diafragmática, sem o aspecto congênito; a internação em unidades que não fossem UTI Neonatal; e a idade no ato de internação igual ou superior a 29 dias. Analisou-se um total de 25.602 prontuários, dos quais 14 corresponderam a HDC. O acometimento por gênero foi de 71,43% masculino (10 casos) e 28,57% feminino (4), com 21,34% das localizações de HDC tipo Bochdalek à direita (3) e 78,57% à esquerda (11). Todos os neonatos deste estudo passaram por ventilação mecânica invasiva (VMI) 9,21 ± 5,55 dias. A cirurgia foi indicada em 11 casos (78,57%), com vias de acesso por toracotomia em 4 (36,36%) e por laparotomia subcostal em 7 (63,64%), todos com uso de dreno torácico homolateral ao hemitórax. O tempo total de internação foi de 19,42 ± 15,36 dias. Observou-se a evolução de alta melhorada em oito pacientes (57,14%) e o óbito de seis (42,86%), com idade de 6,19 ± 4,79 dias, sem referência de acompanhamento do desenvolvimento neuropsicomotor posteriormente. Ocorreram baixas incidências de casos por ano, e o gênero de acometimento, as malformações associadas e o tempo de VMI foram semelhantes a outras populações no mundo.

ABSTRACT The aim of this study is to analyze the clinical and hospital profile of newborns diagnosed with Congenital Diaphragmatic Hernia (CDH) from 2008 to 2018 in a maternal and child reference hospital. It is a cross-sectional and descriptive analytical study, which mainly included data from medical records with the codes Q79.0, Q79.1, J98.6, K44 and K44.0 of the International Classification of Diseases (ICD-10). The exclusion criteria of medical records were the diagnosis of other types of diaphragmatic hernia, without the congenital aspect; hospitalization in units that were not Neonatal ICUs; and the age at admission equal to or greater than 29 days. A total of 25,602 records were analyzed, of which 14 corresponded to CDH. The gender involvement was 71.43% male (10 cases) and 28.57% female (4), with 21.34% of Bochdalek-type CDH located on the right (3) and 78.57% on the left (11). All newborns in this study underwent invasive mechanical ventilation (IMV) 9.21 ± 5.55 days. Surgery was indicated in 11 cases (78.57%), with thoracotomy access routes in four (36.36%) and subcostal laparotomy in seven (63.64%), all using a chest tube homolateral to the hemithorax. The total hospital stay was 19.42 ± 15.36 days. There was an improved discharge evolution in eight patients (57.14%) and the death of six (42.86%), with ages around 6.19 ± 4.79 days, with no follow-up of neuropsychomotor development afterwards. There were low incidences of cases per year, the gender involvement, the associated malformations and the IMV time were similar to other populations in the world.

RESUMEN El objetivo de este estudio es analizar el perfil clínico-hospitalario de neonatos diagnosticados con hernia diafragmática congénita (HDC) en el período de 2008 a 2018 en un hospital de referencia materno-infantil. Este es un estudio transversal, analítico-descriptivo, realizado con base en datos de historias clínicas con los códigos Q79.0, Q79.1, J986, K44 y K44.0 de la Clasificación Internacional de Enfermedades (CIE-10). Los criterios de exclusión de las historias clínicas fueron el diagnóstico de otros tipos de hernia diafragmática sin el aspecto congénito; hospitalización en unidades que no sean UCI neonatales; y edad de ingreso igual o mayor a 29 días. Se analizaron un total de 25.602 registros, de los cuales 14 correspondían a HDC. Entre el género afectado, el 71,43% fue el género masculino (10 casos) y el 28,57% el femenino (4), con un 21,34% de las ubicaciones de la HDC de tipo Bochdalek a la derecha (3) y un 78,57% a la izquierda (11). Todos los recién nacidos en este estudio estuvieron bajo ventilación mecánica invasiva (VMI) por 9,21±5,55 días. La cirugía estuvo indicada para 11 casos (78,57%), con vías de acceso por toracotomía para 4 (36,36%) y laparotomía subcostal para 7 (63,64%), todos con sonda torácica homolateral al hemitórax. La estancia hospitalaria total fue de 19,42±15,36 días. Se observó una mejor evolución del alta en ocho pacientes (57,14%) y muerte de seis (42,86%) con 6,19±4,79 días de edad, sin referencia de seguimiento del desarrollo neuropsicomotor posteriormente. Hubo baja incidencia de casos por año; y el género que acomete, las malformaciones asociadas y el tiempo de VMI fueron similares a otros estudios de la literatura.

Resumo Introdução Hanseníase é uma doença infecciosa que pode levar à incapacidade física. A escala SALSA e a Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF) podem ser úteis no manejo clínico de pacientes com essa doença. Assim, o objetivo foi relacionar a CIF com a limitação de atividade e restrição à participação de indivíduos com hanseníase, utilizando a escala SALSA. Metodologia Tratou-se de um estudo observacional transversal analítico e descritivo, com a utilização da escala SALSA, relacionado aos domínios mobilidade, autocuidado, trabalho e destreza. Após a entrevista realizada com os pacientes, os domínios foram codificados pela CIF segundo os códigos relacionados à atividade e participação. Resultados A amostra foi composta por 30 indivíduos, com média de idade de 38,4, sendo a maioria do gênero masculino. A média do escore da escala SALSA foi de 36,9 pontos, apresentando leve limitação de atividades. Os domínios da escala SALSA e o uso dos códigos da CIF mostraram dificuldade leve a moderada em sua grande maioria, com resultados significantes (p≤0,05). O único domínio que apresentou tarefa com dificuldade completa foi o de mobilidade. Conclusão A escala SALSA mostrou leve limitação de atividade em pacientes com hanseníase, porém, quando relacionado à CIF, apresentou limitações maiores, principalmente no domínio mobilidade.

Abstract Introduction Leprosy is an infectious disease that can lead to physical disability. The SALSA scale and the International Classification of Functioning, Disability and Health (ICF) may be useful in the clinical management of these patients. Thus, the objective was to correlate the ICF with the limitation of activity and restriction to participation for individuals with leprosy, using the SALSA scale. Methodology This was an analytical and descriptive cross-sectional observational study, using the SALSA scale, related to mobility, self-care, work and skill domains. After the interview with the patients, the domains were codified by the ICF, using the codes related to activity and participation. Results The sample consisted of 30 individuals, with a mean age of 38.4, the majority being male. The SALSA scale mean score was 36.9 points, presenting a slight limitation of activities. The SALSA scale domains, together with the use of the ICF codes, show a slight to moderate difficulty in the great majority, with significant results (p≤0.05). The mobility domain was the only one to present task with complete difficulty. Conclusion The SALSA scale showed a slight limitation of activity in patients with leprosy, but when related to ICF, there were larger limitations, especially in the mobility domain.

ABSTRACT We carried out a cross-sectional study from January to December 2015 on 1,425 inhabitants from a floating population in the Brazilian Amazon (Murinin district, Pará State) to describe the population-based prevalence of tuberculosis (TB) from 2011 to 2014, recent TB contacts (rCts) latently infected with Mycobacterium tuberculosis (LTBI) , the coverage of the local health network, socio-environmental factors, and frequency of intestinal parasitic infection (IPI). We found that the sanitary structure was inadequate, with latrines being shared with other rooms within the same accommodation; well water was the main source of water, and 48% of families had low incomes. The average rate of TB was 105/100, 000 inhabitants per year; one third of TB patients had been household contacts of infected individuals in the past, and 23% of rCts were LTBI. More than half (65%) of 44% of the stools examined (representing 76% of the housing) had IPIs; the highest prevalence was of fecal-oral transmitted protozoa (40%, Giardia intestinalis ), followed by soil-transmitted helminths (23%). TB transmission may be related to insufficient disease control of rCts, frequent relocation, and underreporting. Education, adopting hygienic habits, improving sanitation, provision of a treated water supply and efficient sewage system, further comprehensive epidemiological surveillance of those who enter and leave the community and resources for basic treatment of IPIs are crucial in combating the transmission of these neglected diseases.

ResumoObjetivoInvestigar o perfil clínico-epidemiológico de pacientes portadores do HTLV-1 em Belém, no Estado do Pará, Brasil, descrevendo as características de indivíduos infectados e atendidos no Laboratório de Clínica e Epidemiologia de Doenças Endêmicas (LCEDE) do Núcleo de Medicina Tropical (NMT) da Universidade Federal do Pará (UFPA).MetodologiaFoi um estudo descritivo de corte transversal, com coleta em prontuários de pacientes infectados pelo HTLV-1, matriculados no LCEDE do NMT da UFPA entre os anos 2000 a 2012. Foi aplicada a análise descritiva pelo programa Epi Info 3.2.5.ResultadosDos 182 prontuários, 35,2% eram do sexo masculino, e 64,8%, do sexo feminino. Houve predomínio de indivíduos casados (47,8%). A maioria (73,6%) tinha procedência do município de Belém-PA. Dentre os pacientes sintomáticos, 51% apresentavam sintomas neurológicos, 21%, queixas dermatológicas, 18%, queixas reumatológicas, e 10%, queixas autonômicas. Com relação aos pacientes com sintomas neurológicos, 16 (39,0%) foram diagnosticados com PET/MAH.ConclusõesHouve o predomínio do sexo feminino, na faixa etária entre 40 e 49 anos, casado, trabalho informal, procedentes de Belém, com queixas neurológicas e com retorno regular as consultas médicas.

AbstractObjectiveThe clinical-epidemiological profile of patients with HTLV-1 in Belém, Pará state, Brazil was investigated describing the characteristics of these patients at an outpatient service of the Clinical and Epidemiologic Laboratory of Endemic Diseases - LCEDE from the Tropical Medicine Center - NMT of the Federal University of Pará - UFPA.MethodologyIt was a descriptive, cross-sectional study with data collected from the records of HTLV-1 patients from 2000 to 2012. Descriptive analysis used Epi Info 3.2.5 software.ResultsOf the 182 patients, 35.2% were male and 64.8% female, with a predominance of married individuals (47.8%), approximately 73.6% were from Belém. Among the symptomatic patients, 51% presented neurological symptoms, 21% dermatological complaints, 18% rheumatologic complaints, and 10% autonomic complaints. Among the patients with neurological symptoms, 16 (39%) were diagnosed with HAM/TSP.ConclusionThere is predominance of females, aged 40-49 years, married, with informal jobs, from Belém, with neurological sings and regular return to medical visits.

O comprometimento pulmonar é uma das manifestações extra-articulares da artrite reumatóide e pode ser devido à própria doença ou secundário às medicações utilizadas para seu tratamento. Este trabalho relata um caso de uma paciente de 60 anos de idade com diagnóstico de artrite reumatoide que evoluiu com múltiplos nódulos pulmonares durante o tratamento com leflunomida.

Pulmonary involvement is one of the extra-articular manifestations of rheumatoid arthritis and can be due to the disease itself or secondary to the medications used in order to treat it. We report the case of a 60-year-old woman who had been diagnosed with rheumatoid arthritis and developed multiple pulmonary nodules during treatment with leflunomide.

INTRODUCTION: This study aimed to evaluate spasticity in human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients before and after physical therapy using the International Classification of Functioning, Disability and Health (ICF). METHODS: Nine subjects underwent physical therapy. Spasticity was evaluated using the Modified Ashworth Scale. The obtained scores were converted into ICF body functions scores. RESULTS: The majority of subjects had a high degree of spasticity in the quadriceps muscles. According to the ICF codes, the spasticity decreased after 20 sessions of physical therapy. CONCLUSIONS: The ICF was effective in evaluating spasticity in HAM/TSP patients.

O problema tratado nesta pesquisa foi a diferença de aprendizagem observada entre os estudantes de um curso de Planejamento e Controle da Produção (PCP). O objetivo foi descrever e analisar as diferenças de aprendizado segundo os Estilos de Aprendizagem (EdA). Examinaram-se a assimilação e compreensão (notas em provas) e os EdA de 356 aprendizes em 16 turmas de pós-graduação - MBA e Especialização - durante cinco anos. Um jogo de empresas dinamizou as vivências nas quais observou-se maior aprendizado dos estudantes com estilo reflexivo (ativo-reflexivo) ou visual (visualverbal). Ao não explorar a reflexão, o jogo pode ter restringido o ciclo de aprendizagem vivencial, sobretudo dos ativos. Sugerem-se aos educadores duas diretrizes para o desenho educacional: quando padronizado, que se busque balancear as atividades para atender aos diferentes EdA. Quando o desenho for personalizado, que se insiram atividades complementares às preferências do aprendiz, viabilizando uma vivência com equilíbrio entre ação e reflexão.

The problem this study dealt with was the difference in learning observed among students of a Production Control and Planning (PCP) course. The objective was to describe and to analyze the learning differences according to Learning Styles (LS). Assimilation and comprehension (test scores) and the LS of 356 students in 16 graduate classes - MBAs and Extension Courses - from five years were examined. A business game brought the experiences to life, where greater learning was observed among students with a reflective (active-reflective) or visual (visual-verbal) style. By not exploring reflection, the game may have restricted the experience learning cycle, especially among the active ones. Two guidelines for the educational design are suggested for educators: when standardizing the designone should seek to balance activities in order to meet different LS. When the design is personalized, one should insert activities which are complementary to the learner's preferences, thus enabling a balanced experience between action and reflection.

El problema tratado en esta pesquisa fue la diferencia de aprendizaje observada entre los estudiantes de un curso de Planificación y Control de la producción (PCP). El objetivo fue describir y analizar las diferencias de aprendizaje según los Estilos de aprendizaje (EdA). Se examinaron la asimilación y la comprensión (notas en pruebas) y los EdA de 356 aprendices en 16 grupos de postgrado -MBA y Especialización- durante cinco años. Un grupo de empresas dinamizó las vivencias en las cuales se observó un mayor aprendizaje de los estudiantes con estilo reflexivo (activo-reflexivo) o visual (visualverbal). Al no explotar la reflexión el juego puede haber restringido el ciclo de aprendizaje vivencial, sobretodo de los activos. Se sugiere a los educadores dos directivas para el diseño educacional: cuando sea estandarizado y se busque balancear las actividades para atender a los diferentes EdA. Cuando el diseño fuera personalizado, que se incluyan actividades complementarias a las preferencias del aprendiz, viabilizando una vivencia con equilibrio entre la acción y la reflexión.

Good exposure of the preparation margins and haemostasis in the sulcular gingiva are necessary for accurate impressions to produce precise restorations. The use of cordless retraction paste material in implant dentistry is a relatively novel application. However, few studies have been conducted on the use of retraction pastes and their possible interaction with implant surfaces. Recent literature has described remnants on titanium implant surfaces and expressed the need for an assessment of the biocompatibility of the exposed surface (Chang et al.). This in vitro study evaluated the effect of a cordless gingival retraction paste on sterile titanium disks. Surface chemistry was determined using energy-dispersive X-ray spectroscopy (EDS), and further investigated using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). After exposure to retraction paste, surface chemistry alterations were identified. A fibroblast cell line (L929) was exposed to the disks and the live/dead viability/cytotoxicity assay was used to determine any effects on the proliferation and health of cells. The disks exposed to the retraction paste showed fewer dead cells compared to the unexposed disks. This was statistically significant.